Article
Dual-trait genomic analysis in highly stratified Arabidopsis thaliana populations using genome-wide association summary statistics.
Heredity - 1 Jul 2024
Feng Xiao, Zan Yanjun, Li Ting, Yao Yue, Ning Zheng, Li Jiabei, Charati Hadi, Xu Weilin, Wan Qianhui, Zeng Dongyu, Zeng Ziyi, Liu Yang, Shen Xia
Abstract excerpt
Genome-wide association study (GWAS) is a powerful tool to identify genomic loci underlying complex traits. However, the application in natural populations comes with challenges, especially power loss due to population stratification. Here, we introduce a bivariate analysis approach to a GWAS dataset of Arabidopsis thaliana. We demonstrate the efficiency of dual-phenotype analysis to uncover hidden genetic loci...
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