Article
A genetic screen of transcription factors in the Drosophila melanogaster abdomen identifies novel pigmentation genes.
G3 (Bethesda, Md.) - 4 Sept 2024
Petrosky Sarah J, Williams Thomas M, Rebeiz Mark
Abstract excerpt
Gene regulatory networks specify the gene expression patterns needed for traits to develop. Differences in these networks can result in phenotypic differences between organisms. Although loss-of-function genetic screens can identify genes necessary for trait formation, gain-of-function screens can overcome genetic redundancy and identify loci whose expression is sufficient to alter trait formation. Here, we...
Topics
- Animals
- Drosophila melanogaster
- Pigmentation
- Transcription Factors
- Drosophila Proteins
- Abdomen
- Phenotype
- CRISPR-Cas Systems
- Genetic Testing
- Animals, Genetically Modified
- Gene Regulatory Networks