Article
A genome-wide, fine-scale map of natural pigmentation variation in Drosophila melanogaster.
PLoS genetics - 1 Jun 2013
Bastide Héloïse, Betancourt Andrea, Nolte Viola, Tobler Raymond, Stöbe Petra, Futschik Andreas, Schlötterer Christian
Abstract excerpt
Various approaches can be applied to uncover the genetic basis of natural phenotypic variation, each with their specific strengths and limitations. Here, we use a replicated genome-wide association approach (Pool-GWAS) to fine-scale map genomic regions contributing to natural variation in female abdominal pigmentation in Drosophila melanogaster, a trait that is highly variable in natural populations and highly...
Topics
- Animals
- Chromosome Mapping
- Drosophila melanogaster
- Female
- Genetics, Population
- Genome, Insect
- Genome-Wide Association Study
- Phenotype
- Pigmentation
- Polymorphism, Single Nucleotide
- Quantitative Trait Loci
- Regulatory Sequences, Nucleic Acid