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Article

Generation of an induced pluripotent stem cell line (KEIUi008-A) from a hearing loss patient with an A1555G mutation in mitochondrial DNA.

Stem cell research - 1 Aug 2024

Masano Yusuke, Saegusa Chika, Ishikawa Mitsuru, Matsunaga Tatsuo, Okano Hideyuki, Fujioka Masato

Abstract excerpt

We report the establishment of a human induced pluripotent stem cell (iPSC) line from a 54-year-old male patient with an A1555G mutation in the mitochondrial 12S ribosomal RNA gene (MTRNR1), associated with sensorineural hearing loss. The established iPSC line expressed stemness markers or undifferentiated state markers. We also demonstrated the capacity of the cells to differentiate into the three germ layers,...

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Source

Identifiers

PMID: 38815527
DOI: 10.1016/j.scr.2024.103452

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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