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The Cryptosporidium signaling kinase CDPK5 plays an important role in male gametogenesis and parasite virulence

29 May 2024

Abstract excerpt

The protozoan parasite Cryptosporidium is a leading cause of diarrhea in young children. The parasite's life cycle involves a coordinated and timely progression from asexual to sexual stages, leading to the formation of the transmissible oocyst. Underlying molecular signaling mechanisms orchestrating sexual development are not known. Here, we describe the function of a signaling kinase in Cryptosporidium male...

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PMID: 38814783
DOI: 10.1016/j.celrep.2024.114263

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