Article
Virological and Mitochondriopathogical Characteristics of the SARS-CoV-2 Omicron XBB.1.16 Spike.
ACS applied materials & interfaces - 12 Jun 2024
Fang Liaoxin, Kang Xiaofeng, Hong Qian, Xue Chunyuan, Pan Lu, Chen Jiaxin, Tang Chuanhao, Sun Liying, Xu Xiaojie, Yuan Jing, Du Yimeng, Xu An
Abstract excerpt
The emergence of XBB.1.16 has gained rapid global prominence. Previous studies have elucidated that the infection of SARS-CoV-2 induces alterations in the mitochondrial integrity of host cells, subsequently influencing the cellular response to infection. In this study, we compared the differences in infectivity and pathogenicity between XBB.1.16 and the parental Omicron sublineages BA.1 and BA.2 and assessed...
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