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Article

Genomic characterization reveals distinct mutational landscapes and therapeutic implications between different molecular subtypes of triple-negative breast cancer.

Scientific reports - 29 May 2024

Li Ruo Qi, Yan Lei, Zhang Ling, Ma Hai Xia, Wang Hui Wen, Bu Peng, Xi Yan Feng, Lian Jing

Abstract excerpt

Triple-negative breast cancer (TNBC) has high heterogeneity, poor prognosis, and limited treatment success. Recently, an immunohistochemistry-based surrogate classification for the "Fudan University Shanghai Cancer Center (FUSCC) subtyping" has been developed and is considered more suitable for clinical application. Seventy-one paraffin-embedded sections of surgically resected TNBC were classified into four...

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Identifiers

PMID: 38811720
DOI: 10.1038/s41598-024-62991-3
PMCID: PMC11137060

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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