Article
Molecular subtypes of triple-negative breast cancer: understanding of subtype categories and clinical implication.
Genes & genomics - 1 Dec 2020
Lee Yong-Moon, Oh Man Hwan, Go Jai-Hyang, Han Kyudong, Choi Song-Yi
Abstract excerpt
BACKGROUND: Triple-negative breast cancer (TNBC) is a heterogeneous entity that encompasses several subtypes with distinct molecular characteristics. The patients with TNBCs show unpredictable response to the chemotherapy, and further there is the lack of effective agents. Thus, many studies have been underway to discover targeted therapy suitable for patients with specific genetic alterations in each molecular...
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