Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Ferredoxin 1: a gatekeeper in halting lung adenocarcinoma progression through activation of the GPRIN2 signaling pathway

27 May 2024

Abstract excerpt

BACKGROUND: Lung adenocarcinoma (LUAD) is a highly lethal form of lung cancer. Despite advancements in treatments, managing LUAD is still challenging due to its aggressive behavior. Recent studies indicate that various molecular pathways, including the dysregulation of ferredoxin 1 (FDX1), play roles in LUAD progression. FDX1, a crucial protein in cellular redox reactions and energy metabolism, has been linked to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer, Hypoxia, and Metabolism
Share to Ferroptosis and cancer prognosis
Share to Neuroblastoma Research and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38802900
DOI: 10.1186/s12967-024-05277-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Ferredoxin 1: a gatekeeper in halting lung adenocarcinoma progression through activation of the GPRIN2 signaling pathwayPMID 38802900Read ↗

Ferredoxin 1 is a cuproptosis-key gene responsible for tumor immunity and drug sensitivity: A pan-cancer analysisSemantic proximity Read ↗

Pan-cancer analysis reveals the value of FDX1 as a novel biomarker in the prognosis and immunotherapy in human tumorsSemantic proximity Read ↗

Systematic Analysis and Validation of the Prognosis, Immunological Role and Biology Function of the Ferroptosis-Related lncRNA GSEC/miRNA-101-3p/CISD1 Axis in Lung AdenocarcinomaSemantic proximity Read ↗

Down-regulated FDX1 inhibited the proliferation and migration of renal cell carcinoma cellsSemantic proximity Read ↗

Pan-cancer analysis of potential biological function and prognostic value of copper homeostasis related gene ferredoxin-1Semantic proximity Read ↗

Identification of GPX4 as a therapeutic target for lung adenocarcinoma after EGFR-TKI resistanceSemantic proximity Read ↗

Overexpression of TNFSF11 reduces GPX4 levels and increases sensitivity to ferroptosis inducers in lung adenocarcinomaSemantic proximity Read ↗

Characterization of the functional effects of ferredoxin 1 as a cuproptosis biomarker in cancerSemantic proximity Read ↗

Prognostic and immunological role of FDX1 in pan-cancer: an in-silico analysisSemantic proximity Read ↗

KLF11 regulates lung adenocarcinoma ferroptosis and chemosensitivity by suppressing GPX4Semantic proximity Read ↗

Cuproptosis-Related Gene FDX1 Suppresses the Growth and Progression of Colorectal Cancer by Retarding EMT ProgressSemantic proximity Read ↗

Glutaredoxin‐1 promotes lymphangioleiomyomatosis progression through inhibiting Bim‐mediated apoptosis via COX2/PGE2/ERK pathwaySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.