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Ferredoxin 1 is a cuproptosis-key gene responsible for tumor immunity and drug sensitivity: A pan-cancer analysis

21 Sept 2022

Abstract excerpt

Ferredoxin 1 (FDX1) functions by transferring electrons from NADPH to mitochondrial cytochrome P450 via the ferredoxin reductase and is the key regulator in copper-dependent cell death. Although mounting evidence supports a vital role for FDX1 in tumorigenesis of some cancers, no pan-cancer analysis of FDX1 has been reported. Therefore, we aimed to explore the prognostic value of FDX1 in pan-cancer and...

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Share to Epigenetics and DNA Methylation
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PMID: 36210836
DOI: 10.3389/fphar.2022.938134

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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