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Prognostic and immunological role of FDX1 in pan-cancer: an in-silico analysis

16 May 2023

Abstract excerpt

Previous research has demonstrated that ferredoxin 1 (FDX1) contributes to the accumulation of toxic lipoylated dihydrolipoamide S-acetyltransferase (DLAT) and results in cuproptotic cell death. However, the role that FDX1 plays in human cancer prognosis and immunology is still not well understood. The original data was obtained from TCGA and GEO databases and integrated using R 4.1.0. The TIMER2.0, GEPIA, and...

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PMID: 37193786
DOI: 10.1038/s41598-023-34752-1

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