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Article

Use of biologics in Chinese pregnant patients with deficiency of interleukin-36 receptor antagonist (DITRA): A case series.

Taiwanese journal of obstetrics & gynecology - 1 May 2024

Hsieh Chang-Yu, Tsai Yun-Ju, Tsai Tsen-Fang

Abstract excerpt

OBJECTIVE: Impetigo herpetiformis (IH) is a rare form of pustular psoriasis which may result in maternal and fetal morbidity and even mortality. Deficiency of interleukin-36 receptor antagonist (DITRA) is the most frequently identified genetic defect of IH. Currently there are no biologics approved for IH despite the revolutionary role of biologics in the treatment of plaque and pustular psoriasis. Anecdotal...

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PMID: 38802208
DOI: 10.1016/j.tjog.2024.02.001

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