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Article

CRF08_BC subtype is more prone to ART failure and new-generation NNRTI-resistance under long-term first-line ART.

International journal of antimicrobial agents - 1 Aug 2024

Wu Min, Dong Yuan, Zeng Liyan, Lin Yi, Yao Liang, Zhang Yong, Sun Weiwei, Sun Jianjun, Wang Qianqian, Yuan Dan, Xiao Hong

Abstract excerpt

OBJECTIVE: To investigate the characteristics of drug resistance mutations (DRMs) and their contextual influence on drug susceptibility in CRF07_BC and CRF_08BC subtypes. METHODS: Patients with virological failure were genotyped using phylogenetic analysis. DRMs and susceptibility to antiretroviral drugs were analysed using the Stanford University HIV Drug Resistance Database. RESULTS: Six HIV subtypes were...

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Identifiers

PMID: 38795930
DOI: 10.1016/j.ijantimicag.2024.107215

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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