Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

NeMu: a comprehensive pipeline for accurate reconstruction of neutral mutation spectra from evolutionary data.

Nucleic acids research - 5 Jul 2024

Efimenko Bogdan, Popadin Konstantin, Gunbin Konstantin

Abstract excerpt

The recognized importance of mutational spectra in molecular evolution is yet to be fully exploited beyond human cancer studies and model organisms. The wealth of intraspecific polymorphism data in the GenBank repository, covering a broad spectrum of genes and species, presents an untapped opportunity for detailed mutational spectrum analysis. Existing methods fall short by ignoring intermediate substitutions on...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Evolution, Molecular
Share to Mutation
Share to Phylogeny

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Software

Source

Open in PubMed Open full text

Identifiers

PMID: 38795067
DOI: 10.1093/nar/gkae438
PMCID: PMC11223800

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

NeMu: a comprehensive pipeline for accurate reconstruction of neutral mutation spectra from evolutionary data.PMID 38795067Read ↗

Fine-tuning germline mutation rates across evolution.Semantic proximity Read ↗

The evolution and convergence of mutation spectra across mammalsSemantic proximity Read ↗

Somatic and germline mutational processes across the tree of lifeSemantic proximity Read ↗

Phylomedicine: an evolutionary telescope to explore and diagnose the universe of disease mutations.Semantic proximity Read ↗

Somatic and germline mutational processes across the tree of lifeSemantic proximity Read ↗

Intrinsic base substitution patterns in diverse species reveal links to cancer and metabolism.Semantic proximity Read ↗

The challenge and promise of estimating the de novo mutation rate from whole-genome comparisons among closely related individuals.Semantic proximity Read ↗

Methylation-associated mutagenesis underlies variation in the mutation spectrum across eukaryotes.Semantic proximity Read ↗

Experimental estimates of germline mutation rate in eukaryotes: a phylogenetic meta-analysisSemantic proximity Read ↗

Mutation-Simulator: fine-grained simulation of random mutations in any genome.Semantic proximity Read ↗

mutyper: assigning and summarizing mutation types for analyzing germline mutation spectraSemantic proximity Read ↗

Alleleomes characterize the survivors of 3.5 billion years of bacterial evolutionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.