Article
Apolipoprotein-CIII O-Glycosylation Is Associated with Micro- and Macrovascular Complications of Type 2 Diabetes.
International journal of molecular sciences - 14 May 2024
Naber Annemieke, Demus Daniel, Slieker Roderick C, Nicolardi Simone, Beulens Joline W J, Elders Petra J M, Lieverse Aloysius G, Sijbrands Eric J G, 't Hart Leen M, Wuhrer Manfred, van Hoek Mandy
Abstract excerpt
Apolipoprotein-CIII (apo-CIII) inhibits the clearance of triglycerides from circulation and is associated with an increased risk of diabetes complications. It exists in four main proteoforms: O-glycosylated variants containing either zero, one, or two sialic acids and a non-glycosylated variant. O-glycosylation may affect the metabolic functions of apo-CIII. We investigated the associations of apo-CIII...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
