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Article

The relationship between BDNF and physical activity on depression.

Progress in neuro-psychopharmacology & biological psychiatry - 30 Aug 2024

Zarza-Rebollo Juan Antonio, López-Isac Elena, Rivera Margarita, Gómez-Hernández Laura, Pérez-Gutiérrez Ana M, Molina Esther

Abstract excerpt

BACKGROUND/OBJECTIVE: Major depressive disorder (MDD) is one of the leading causes of disease burden and disability worldwide. Brain-derived neurotrophic factor (BDNF) seems to have an important role in the molecular mechanisms underlying MDD aetiology, given its implication in regulating neuronal plasticity. There is evidence that physical activity (PA) improves depressive symptoms, with a key role of BDNF in...

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Identifiers

PMID: 38788892
DOI: 10.1016/j.pnpbp.2024.111033

Genes

BDNF

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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