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Article

The BDNF Val66Met polymorphism does not moderate the effect of self-reported physical activity on depressive symptoms in midlife.

Psychiatry research - 15 Aug 2014

Gujral Swathi, Manuck Stephen B, Ferrell Robert E, Flory Janine D, Erickson Kirk I

Abstract excerpt

The brain-derived neurotrophic factor (BDNF) Val66Met single nucleotide polymorphism may be associated with clinical and subsyndromal depression, but physical activity improves mood and increases BDNF expression. The aim of the study was to examine whether the BDNF polymorphism moderates an effect of physical activity on depressive symptoms. BDNF genotype, physical activity measured by the Paffenbarger...

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Identifiers

PMID: 24745471
DOI: 10.1016/j.psychres.2014.03.028
PMCID: PMC4059542

Genes

BDNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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