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Article

Unraveling genetic causality between metformin and myocardial infarction on the basis of Mendelian randomization.

Frontiers in endocrinology - 1 Jan 2024

Zhuang Yongru, Pan Xiaojun, Chen Ya, Song Jinfang

Abstract excerpt

Background: In recent years, several studies have explored the effect of metformin on myocardial infarction (MI), but whether metformin has an improvement effect in patients with MI is controversial. This study was aimed to investigate the causal relationship between metformin and MI using Mendelian randomization (MR) analysis. Methods: The genome-wide significant (P<5×10-8) single-nucleotide polymorphisms (SNPs)...

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Identifiers

PMID: 38765955
DOI: 10.3389/fendo.2024.1376464
PMCID: PMC11099286

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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