Article
Causal association between metformin and arrhythmias: A Mendelian randomization study.
Medicine - 9 Jan 2026
Qin Wen-Pei, Zhang Jin-Yu, Zhao Qian, Liu Fen, Li Xiao-Mei, Yang Yi-Ning
Abstract excerpt
There is ongoing discussion in the medical community on the effect of metformin in cardiac arrhythmias. Investigating the causal relationship between metformin and arrhythmias was the target of the research. We utilized the Mendelian randomization (MR)-based platform to collect genome-wide association data linking arrhythmias and metformin. We utilized SNPs connected to metformin as instrumental variables (IVs)...
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