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Article

Defects in diffusion barrier function of ciliary transition zone caused by ciliopathy variations of TMEM218.

Human molecular genetics - 6 Aug 2024

Fujii Taiju, Liang Luxiaoxue, Nakayama Kazuhisa, Katoh Yohei

Abstract excerpt

Primary cilia are antenna-like structures protruding from the surface of various eukaryotic cells, and have distinct protein compositions in their membranes. This distinct protein composition is maintained by the presence of the transition zone (TZ) at the ciliary base, which acts as a diffusion barrier between the ciliary and plasma membranes. Defects in cilia and the TZ are known to cause a group of disorders...

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Identifiers

PMID: 38751342
DOI: 10.1093/hmg/ddae083

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Defects in diffusion barrier function of ciliary transition zone caused by ciliopathy variations of TMEM218.PMID 38751342Read ↗

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