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Article

Evolution of a novel adrenal cell type that promotes parental care.

Nature - 1 May 2024

Niepoth Natalie, Merritt Jennifer R, Uminski Michelle, Lei Emily, Esquibies Victoria S, Bando Ina B, Hernandez Kimberly, Gebhardt Christoph, Wacker Sarah A, Lutzu Stefano, Poudel Asmita, Soma Kiran K, Rudolph Stephanie, Bendesky Andres

Abstract excerpt

Cell types with specialized functions fundamentally regulate animal behaviour, and yet the genetic mechanisms that underlie the emergence of novel cell types and their consequences for behaviour are not well understood1. Here we show that the monogamous oldfield mouse (Peromyscus polionotus) has recently evolved a novel cell type in the adrenal gland that expresses the enzyme AKR1C18, which converts progesterone...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 38750354
DOI: 10.1038/s41586-024-07423-y
PMCID: PMC11329292

Genes

GADD45A

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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