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Body mass index and all-cause mortality in HUNT and UK biobank studies: revised non-linear Mendelian randomisation analyses

1 May 2024

Abstract excerpt

Objectives To estimate the shape of the causal relationship between body mass index (BMI) and mortality risk in a Mendelian randomisation framework. Design Mendelian randomisation analyses of two prospective population-based cohorts. Setting Individuals of European ancestries living in Norway or the UK. Participants 56 150 participants from the Trøndelag Health Study (HUNT) in Norway and 366 385 participants from...

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PMID: 38749693
DOI: 10.1136/bmjopen-2023-081399

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