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Article

Common variation in a long non-coding RNA gene modulates variation of circulating TGF-β2 levels in metastatic colorectal cancer patients (Alliance).

BMC genomics - 14 May 2024

Quintanilha Julia C F, Sibley Alexander B, Liu Yingmiao, Niedzwiecki Donna, Halabi Susan, Rogers Layne, O'Neil Bert, Kindler Hedy, Kelly William, Venook Alan, McLeod Howard L, Ratain Mark J, Nixon Andrew B, Innocenti Federico, Owzar Kouros

Abstract excerpt

BACKGROUND: Herein, we report results from a genome-wide study conducted to identify protein quantitative trait loci (pQTL) for circulating angiogenic and inflammatory protein markers in patients with metastatic colorectal cancer (mCRC). The study was conducted using genotype, protein marker, and baseline clinical and demographic data from CALGB/SWOG 80405 (Alliance), a randomized phase III study designed to...

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Identifiers

PMID: 38745123
DOI: 10.1186/s12864-024-10354-7
PMCID: PMC11092225

Genes

EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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