Article
Discovery of PELATON links to the INHBA gene in the TGF-β pathway in colorectal cancer using a combination of bioinformatics and experimental investigations.
International journal of biological macromolecules - 1 Jun 2024
Abutalebi Maryam, Li Dabing, Ahmad Waqar, Mokhtari Khatere, Entezari Maliheh, Hashemi Mehrdad, Fu Junjiang, Maghsoudloo Mazaher
Abstract excerpt
Colorectal cancer (CRC) is a major worldwide health issue, with high rates of both occurrence and mortality. Dysregulation of the transforming growth factor-beta (TGF-β) signaling pathway is recognized as a pivotal factor in CRC pathogenesis. Notably, the INHBA gene and long non-coding RNAs (lncRNAs) have emerged as key contributors to CRC progression. The aim of this research is to explore the immunological...
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