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Impact of PD-L1 Gene Polymorphisms and Interactions with Cooking with Solid Fuel Exposure on Tuberculosis.

Public health genomics - 1 Jan 2024

Tang Kun, Wang Jing, Zhong Hua, Wang Qiaozhi, Li Zihao, Wu Chunli, An Rongjing, Lin Ying, Tan Hongzhuan, Chen Lizhang, Wang Mian, Chen Mengshi

Abstract excerpt

INTRODUCTION: Given that PD-L1 is a crucial immune checkpoint in regulating T-cell responses, the aim of this study was to explore the impact of PD-L1 gene polymorphisms and the interaction with cooking with solid fuel on susceptibility to tuberculosis (TB) in Chinese Han populations. METHODS: A total of 503 TB patients and 494 healthy controls were enrolled in this case-control study. Mass spectrometry...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 38735285
DOI: 10.1159/000538904

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