T2-FLAIR Mismatch: An Imaging Biomarker for Children's MYB/MYBL1-Altered Diffuse Astrocytoma or Angiocentric Glioma.

doi:10.3174/ajnr.A8203

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Article

T2-FLAIR Mismatch: An Imaging Biomarker for Children's MYB/MYBL1-Altered Diffuse Astrocytoma or Angiocentric Glioma.

AJNR. American journal of neuroradiology - 7 Jun 2024

van Maren E A, Dankbaar J W, Wesseling P, Plasschaert S, Muhlebner A, Hoving E W, Robe P A, Snijders T J, Hoogendijk R, Kranendonk M E G, Lequin M H

Abstract excerpt

BACKGROUND AND PURPOSE: T2-FLAIR mismatch is a highly specific imaging biomarker of IDH-mutant diffuse astrocytoma in adults. It has however also been described in MYB/MYBL1-altered low grade tumors. Our aim was to assess the diagnostic power of the T2-FLAIR mismatch in IDH-mutant astrocytoma and MYB/MYBL1-altered low-grade tumors in children and correlate this mismatch with histology. MATERIALS AND METHODS: We...

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PMID: 38724203
DOI: 10.3174/ajnr.A8203
PMCID: PMC11288608

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