Multiomic analysis of uterine leiomyomas in self-described Black and White women: molecular insights into health disparities.

doi:10.1016/j.ajog.2024.04.051

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Article

Multiomic analysis of uterine leiomyomas in self-described Black and White women: molecular insights into health disparities.

American journal of obstetrics and gynecology - 1 Sept 2024

Bateman Nicholas W, Abulez Tamara, Tarney Christopher M, Bariani Maria V, Driscoll Jordan A, Soltis Anthony R, Zhou Ming, Hood Brian L, Litzi Tracy, Conrads Kelly A, Jackson Amanda, Oliver Julie, Ganakammal Satishkumar Ranganathan, Schneider Frank, Dalgard Clifton L, Wilkerson Matthew D, Smith Barbara, Borda Victor, O'Connor Timothy, Segars James, Shobeiri S Abbas, Phippen Neil T, Darcy Kathleen M, Al-Hendy Ayman, Conrads Thomas P, Maxwell George Larry

Abstract excerpt

BACKGROUND: Black women are at an increased risk of developing uterine leiomyomas and experiencing worse disease prognosis than White women. Epidemiologic and molecular factors have been identified as underlying these disparities, but there remains a paucity of deep, multiomic analysis investigating molecular differences in uterine leiomyomas from Black and White patients. OBJECTIVE: To identify molecular...

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PMID: 38723985
DOI: 10.1016/j.ajog.2024.04.051

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MED12

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