Article
MPH: fast REML for large-scale genome partitioning of quantitative genetic variation.
Bioinformatics (Oxford, England) - 2 May 2024
Jiang Jicai
Abstract excerpt
MOTIVATION: Genome partitioning of quantitative genetic variation is useful for dissecting the genetic architecture of complex traits. However, existing methods, such as Haseman-Elston regression and linkage disequilibrium score regression, often face limitations when handling extensive farm animal datasets, as demonstrated in this study. RESULTS: To overcome this challenge, we present MPH, a novel software tool...
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