Article
Inflammatory cytokine profiles in erectile dysfunction: a bidirectional Mendelian randomization.
Frontiers in immunology - 1 Jan 2024
Liu Dongze, Qin Zheng, Yi Bocun, Xie Hongbo, Liang Yunan, Zhu Liang, Yang Kuo, Zhang Hongtuan
Abstract excerpt
Objectives: Inflammatory cytokines (ICs) play an important role in erectile dysfunction (ED). Previous studies have demonstrated that most ED patients have high levels of tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6) and interleukin-8 (IL-8). The causality between 41 ICs and ED is investigated using the Mendelian randomization (MR) approach. Methods: Single nucleotide polymorphisms (SNPs) exposure data of...
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