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Article

Association between MCU Gene Polymorphisms with Obesity: Findings from the All of Us Research Program.

Genes - 19 Apr 2024

Avery Jade, Leak-Johnson Tennille, Francis Sharon C

Abstract excerpt

Obesity is a public health crisis, and its prevalence disproportionately affects African Americans in the United States. Dysregulation of organelle calcium homeostasis is associated with obesity. The mitochondrial calcium uniporter (MCU) complex is primarily responsible for mitochondrial calcium homeostasis. Obesity is a multifactorial disease in which genetic underpinnings such as single-nucleotide polymorphisms...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38674446
DOI: 10.3390/genes15040512
PMCID: PMC11050077

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