Article
Unveiling the role of FTO polymorphisms in predicting response to immune checkpoint inhibitors: A retrospective study.
International immunopharmacology - 30 May 2024
Liu Wenhui, Xiao Chenlin, Luo Jianquan, Liu Mouze, Sun Bao, Luo Zhiying
Abstract excerpt
BACKGROUND: Identifying patients who can benefit from immune checkpoint inhibitors (ICIs) is a critical challenge in immunotherapy. This study aimed to investigate the association between fat mass and obesity-associated protein (FTO) polymorphisms and ICIs treatment outcomes. METHOD: This retrospective study was conducted on 371 patients with malignant tumors who received ICIs treatment and were followed-up for a...
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