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Zeaxanthin epoxidase 3 Knockout Mutants of the Model Diatom Phaeodactylum tricornutum Enable Commercial Production of the Bioactive Carotenoid Diatoxanthin.

Marine drugs - 19 Apr 2024

Græsholt Cecilie, Brembu Tore, Volpe Charlotte, Bartosova Zdenka, Serif Manuel, Winge Per, Nymark Marianne

Abstract excerpt

Carotenoids are pigments that have a range of functions in human health. The carotenoid diatoxanthin is suggested to have antioxidant, anti-inflammatory and chemo-preventive properties. Diatoxanthin is only produced by a few groups of microalgae, where it functions in photoprotection. Its large-scale production in microalgae is currently not feasible. In fact, rapid conversion into the inactive pigment...

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Carotenoids
CRISPR-Cas Systems
Diatoms
Gene Knockout Techniques
Microalgae

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Oxidoreductases

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PMID: 38667802
DOI: 10.3390/md22040185
PMCID: PMC11051370

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