Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Lysosomal genes contribute to Parkinson’s disease near agriculture with high intensity pesticide use

25 Apr 2024

Abstract excerpt

Parkinson's disease (PD), the second most common neurodegenerative disorder, develops sporadically, likely through a combination of polygenic and environmental factors. Previous studies associate pesticide exposure and genes involved in lysosomal function with PD risk. We evaluated the frequency of variants in lysosomal function genes among patients from the Parkinson's, Environment, and Genes (PEG) study with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autophagy in Disease and Therapy
Share to Lysosomal Storage Disorders Research
Share to Parkinson's Disease Mechanisms and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38664407
DOI: 10.1038/s41531-024-00703-4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Lysosomal genes contribute to Parkinson’s disease near agriculture with high intensity pesticide usePMID 38664407Read ↗

Commentary: Pesticides and GBA1 pathogenic variants in Parkinson's disease: An emerging and potentially dangerous association.Semantic proximity Read ↗

Elucidating Conserved Transcriptional Networks Underlying Pesticide Exposure and Parkinson's Disease: A Focus on Chemicals of Epidemiological RelevanceSemantic proximity Read ↗

Genome-wide gene-environment interaction analysis of pesticide exposure and risk of Parkinson's disease.Semantic proximity Read ↗

Occupational Pesticide Exposure in Parkinson’s Disease Related to GBA and LRRK2 VariantsSemantic proximity Read ↗

Genetic variability in pathways associates with pesticide-induced nervous system disease in the United StatesSemantic proximity Read ↗

Pesticides that inhibit the ubiquitin-proteasome system: effect measure modification by genetic variation in SKP1 in Parkinson׳s disease.Semantic proximity Read ↗

Coupling comprehensive pesticide-wide association study to iPSC dopaminergic screening identifies and classifies Parkinson-relevant pesticidesSemantic proximity Read ↗

The interplay between environmental and genetic factors in Parkinson's disease susceptibility: the evidence for pesticides.Semantic proximity Read ↗

Dual-Risk axis: GBA1 mutations and occupational pesticide exposure in Parkinson's disease.Semantic proximity Read ↗

Mechanisms of Gene-Environment Interactions in Parkinson's Disease.Semantic proximity Read ↗

Data-Driven Characterization of Genetic Variability in Disease Pathways and Pesticide-Induced Nervous System Disease in the United States Population.Semantic proximity Read ↗

Genome-wide analysis reveals genes mediating resistance to paraquat neurodegeneration in <i>Drosophila</i>Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.