Article
A High-Coverage Mesolithic Aurochs Genome and Effective Leveraging of Ancient Cattle Genomes Using Whole Genome Imputation.
Molecular biology and evolution - 3 May 2024
Erven Jolijn A M, Scheu Amelie, Verdugo Marta Pereira, Cassidy Lara, Chen Ningbo, Gehlen Birgit, Street Martin, Madsen Ole, Mullin Victoria E
Abstract excerpt
Ancient genomic analyses are often restricted to utilizing pseudohaploid data due to low genome coverage. Leveraging low-coverage data by imputation to calculate phased diploid genotypes that enables haplotype-based interrogation and single nucleotide polymorphism (SNP) calling at unsequenced positions is highly desirable. This has not been investigated for ancient cattle genomes despite these being compelling...
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