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Toxoplasma gondii suppresses proliferation and migration of breast cancer cells by regulating their transcriptome

23 Apr 2024

Abstract excerpt

BACKGROUND: Breast cancer is the most common cancer in women worldwide. Toxoplasma gondii (T. gondii) has shown anticancer activity in breast cancer mouse models, and exerted beneficial effect on the survival of breast cancer patients, but the mechanism was unclear. METHODS: The effect of tachyzoites of T. gondii (RH and ME49 strains) on human breast cancer cells (MCF-7 and MDA-MB-231 cells) proliferation and...

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PMID: 38654350
DOI: 10.1186/s12935-024-03333-1

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