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Catalytic specificity and crystal structure of cystathionine γ-lyase from Pseudomonas aeruginosa

23 Apr 2024

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Abstract The escalating drug resistance among microorganisms underscores the urgent need for innovative therapeutic strategies and a comprehensive understanding of bacteria's defense mechanisms against oxidative stress and antibiotics. Among the recently discovered barriers, the endogenous production of hydrogen sulfide (H 2 S) via the reverse transsulfuration pathway, emerges as a noteworthy factor. In this...

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PMID: 38654065
DOI: 10.1038/s41598-024-57625-7

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