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Article

Associations of dietary sugars with liver stiffness in Latino adolescents with obesity differ on PNPLA3 and liver disease severity.

Liver international : official journal of the International Association for the Study of the Liver - 1 Aug 2024

Schenker Rachel B, Machle Christopher J, Schmidt Kelsey A, Allayee Hooman, Kohli Rohit, Goran Michael I

Abstract excerpt

Metabolic dysfunction-associated steatotic liver disease (MASLD) is the most common paediatric liver disease. Latinos have high MASLD risk due to 50% prevalence of GG genotype of PNPLA3. Our primary aim was to evaluate associations between dietary carbohydrates/sugars and liver stiffness in Latino adolescents with obesity. Our secondary aim was to examine effect modification by (a) PNPLA3 genotype or (b) liver...

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Source

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Identifiers

PMID: 38634702
DOI: 10.1111/liv.15946
PMCID: PMC11251846

Genes

PNPLA3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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