Article
Buffering Mechanism in Aortic Arch Artery Formation and Congenital Heart Disease
15 Apr 2024
Abstract excerpt
BACKGROUND: The resiliency of embryonic development to genetic and environmental perturbations has been long appreciated; however, little is known about the mechanisms underlying the robustness of developmental processes. Aberrations resulting in neonatal lethality are exemplified by congenital heart disease arising from defective morphogenesis of pharyngeal arch arteries (PAAs) and their derivatives. METHODS:...
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