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Article

The Role of Functional Amyloids in Bacterial Virulence

13 Jul 2018

Abstract excerpt

Amyloid fibrils are best known as a product of human and animal protein misfolding disorders, where amyloid formation is associated with cytotoxicity and disease. It is now evident that for some proteins, the amyloid state constitutes the native structure and serves a functional role. These functional amyloids are proving widespread in bacteria and fungi, fulfilling diverse functions as structural components in...

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PMID: 30009771
DOI: 10.1016/j.jmb.2018.07.010

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