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Article

Shorter telomere length increases the risk of lymphocyte immunodeficiency: A Mendelian randomization study

1 Apr 2024

Abstract excerpt

BACKGROUND: For a long time, the prevailing viewpoint suggests that shorter telomere contribute to chromosomal instability, which is a shared characteristic of both aging and cancer. The newest research presented that T cell immune deficiency rather than chromosome instability predisposes patients with short telomere syndromes to some cancers. However, the relationship between genetically determined telomere...

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PMID: 38607251
DOI: 10.1002/iid3.1251

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