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Article

Unraveling Desmin's Head Domain Structure and Function.

Cells - 29 Mar 2024

Vlachakis Dimitrios, Tsilafakis Konstantinos, Kostavasili Ioanna, Kossida Sophia, Mavroidis Manolis

Abstract excerpt

Understanding the structure and function of intermediate filaments (IFs) is necessary in order to explain why more than 70 related IF genes have evolved in vertebrates while maintaining such dramatically tissue-specific expression. Desmin is a member of the large multigene family of IF proteins and is specifically expressed in myocytes. In an effort to elucidate its muscle-specific behavior, we have used a yeast...

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Identifiers

PMID: 38607042
DOI: 10.3390/cells13070603
PMCID: PMC11012097

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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