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Comparative molecular profiling of pancreatic ductal adenocarcinoma of the head versus body and tail

6 Apr 2024

Abstract excerpt

Pancreatic ductal adenocarcinoma (PDAC) of the head (H) and body/tail (B/T) differ in embryonic origin, cell composition, blood supply, lymphatic and venous drainage, and innervation. We aimed to compare the molecular and tumor immune microenvironment (TIME) profiles of PDAC of the H vs. B/T. A total of 3499 PDAC samples were analyzed via next-generation sequencing (NGS) of RNA (whole transcriptome, NovaSeq), DNA...

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PMID: 38582894
DOI: 10.1038/s41698-024-00571-4

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