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Retrospective cohort study of the MTHFR C677T/A1298C polymorphisms and human homocysteine levels in Helicobacter pylori infection.

Diagnostic microbiology and infectious disease - 1 Jul 2024

Oliveira Andreza Paloma Góes, de Matos Gyselly de Cassia Bastos, Vieira Marcelo Cleyton da Silva, Corvelo Tereza Cristina de Oliveira

Abstract excerpt

This study avalited relationship between human Methylenetetrahydrofolate reductase (MTHFR) gene (C677T(rs1801133)/A1298C(rs1801131)) variants and homocysteine levels in 168 patients who are infected with Helicobacter pylori, diagnosed to PCR analysis. PCR-RFLP methods were performed to characterize the MTHFR gene C677T/A1298C variants in DNA samples obtained from gastric biopsies this patients. An...

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PMID: 38579505
DOI: 10.1016/j.diagmicrobio.2024.116243

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