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Article

Predicting immunotherapy response in melanoma using a novel tumor immunological phenotype-related gene index.

Frontiers in immunology - 1 Jan 2024

Zheng Shaoluan, He Anqi, Chen Chenxi, Gu Jianying, Wei Chuanyuan, Chen Zhiwei, Liu Jiaqi

Abstract excerpt

Introduction: Melanoma is a highly aggressive and recurrent form of skin cancer, posing challenges in prognosis and therapy prediction. Methods: In this study, we developed a novel TIPRGPI consisting of 20 genes using Univariate Cox regression and the LASSO algorithm. The high and low-risk groups based on TIPRGPI exhibited distinct mutation profiles, hallmark pathways, and immune cell infiltration in the tumor...

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Source

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Identifiers

PMID: 38571962
DOI: 10.3389/fimmu.2024.1343425
PMCID: PMC10987686

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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