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Mesothelin promotes brain metastasis of non-small cell lung cancer by activating MET

3 Apr 2024

Abstract excerpt

BACKGROUND: Brain metastasis (BM) is common among cases of advanced non-small cell lung cancer (NSCLC) and is the leading cause of death for these patients. Mesothelin (MSLN), a tumor-associated antigen expressed in many solid tumors, has been reported to be involved in the progression of multiple tumors. However, its potential involvement in BM of NSCLC and the underlying mechanism remain unknown. METHODS: The...

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PMID: 38570866
DOI: 10.1186/s13046-024-03015-w

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