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Map-1a regulates Sertoli cell BTB dynamics through the cytoskeletal organization of microtubule and F-actin

3 Apr 2024

Abstract excerpt

Microtubule-associated protein 1a (Map1a) is a microtubule (MT) regulatory protein that binds to the MT protofilaments in mammalian cells to promote MT stabilization. Maps work with MT cleavage proteins and other MT catastrophe-inducing proteins to confer MT dynamics to support changes in the Sertoli cell shape to sustain spermatogenesis. However, no functional studies are found in the literature to probe its...

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PMID: 38570783
DOI: 10.1186/s12958-024-01204-y

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