Article
Emergence of Acquired Dolutegravir Resistance in Treatment-experienced People With HIV in Lesotho.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 22 Nov 2024
Tschumi Nadine, Lukau Blaise, Tlali Katleho, Motaboli Lipontso, Kao Mpho, Kopo Mathebe, Haenggi Kathrin, Mokebe Moleboheng, Naegele Klaudia, Ayakaka Irene, Leuzinger Karoline, Brown Jennifer A, Labhardt Niklaus D
Abstract excerpt
BACKGROUND: Since 2019, the World Health Organization has recommended dolutegravir-based antiretroviral therapy (ART) as the preferred regimen for human immunodeficiency virus management. Large-scale programmatic transitioning to dolutegravir-based ART was subsequently implemented across Africa, often in the absence of recent viral load testing and without access to genotypic resistance testing (GRT) in case of...
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