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Article

Prioritize Variant Reclassification in Pediatric Long QT Syndrome-Time to Revisit.

Pediatric cardiology - 1 Jun 2024

Leung Hei-To, Kwok Sit-Yee, Kwong Ka-Yee, Shih Fong-Ying, Tsao Sabrina, Chung Brian Hon-Yin

Abstract excerpt

Congenital long QT syndrome (LQTS) is an inherited arrhythmia syndrome associated with sudden cardiac death. Accurate interpretation and classification of genetic variants in LQTS patients are crucial for effective management. All patients with LQTS with a positive genetic test over the past 18 years (2002-2020) in our single tertiary pediatric cardiac center were identified. Reevaluation of the reported variants...

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PMID: 38565666
DOI: 10.1007/s00246-024-03461-5

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