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A novel fast hybrid capture sequencing method for high-efficiency common human coronavirus whole-genome acquisition

2 Apr 2024

Abstract excerpt

Rapid and accurate sequencing of the entire viral genome, coupled with continuous monitoring of genetic changes, is crucial for understanding the epidemiology of coronaviruses. We designed a novel method called micro target hybrid capture system (MT-Capture) to enable whole-genome sequencing in a timely manner. The novel design of probes used in target binding exhibits a unique and synergistic "hand-in-hand"...

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PMID: 38564711
DOI: 10.1128/msystems.01222-23

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