Article
Targeted genomic sequencing with probe capture for discovery and surveillance of coronaviruses in bats.
eLife - 8 Nov 2022
Kuchinski Kevin S, Loos Kara D, Suchan Danae M, Russell Jennifer N, Sies Ashton N, Kumakamba Charles, Muyembe Francisca, Mbala Kingebeni Placide, Ngay Lukusa Ipos, N'Kawa Frida, Atibu Losoma Joseph, Makuwa Maria, Gillis Amethyst, LeBreton Matthew, Ayukekbong James A, Lerminiaux Nicole A, Monagin Corina, Joly Damien O, Saylors Karen, Wolfe Nathan D, Rubin Edward M, Muyembe Tamfum Jean J, Prystajecky Natalie A, McIver David J, Lange Christian E, Cameron Andrew D S
Abstract excerpt
Public health emergencies like SARS, MERS, and COVID-19 have prioritized surveillance of zoonotic coronaviruses, resulting in extensive genomic characterization of coronavirus diversity in bats. Sequencing viral genomes directly from animal specimens remains a laboratory challenge, however, and most bat coronaviruses have been characterized solely by PCR amplification of small regions from the best-conserved...
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